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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GRM2
All Species:
40.3
Human Site:
S212
Identified Species:
73.89
UniProt:
Q14416
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14416
NP_000830.2
872
95568
S212
T
Y
V
S
T
V
A
S
E
G
D
Y
G
E
T
Chimpanzee
Pan troglodytes
A3QNZ8
839
95029
R172
S
A
I
G
D
E
L
R
D
K
V
R
F
P
A
Rhesus Macaque
Macaca mulatta
A3QP01
839
95041
R172
S
A
I
S
D
E
L
R
D
K
V
R
F
P
A
Dog
Lupus familis
XP_541867
872
95696
S212
T
Y
V
S
T
V
A
S
E
G
D
Y
G
E
T
Cat
Felis silvestris
Mouse
Mus musculus
Q14BI2
872
95869
S212
T
Y
V
S
T
V
A
S
E
G
D
Y
G
E
T
Rat
Rattus norvegicus
P31421
872
95755
S212
T
Y
V
S
T
V
A
S
E
G
D
Y
G
E
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001518731
870
95758
S212
T
Y
V
S
T
V
A
S
E
G
D
Y
G
E
T
Chicken
Gallus gallus
XP_416842
879
98936
S218
T
Y
V
S
T
V
A
S
E
G
D
Y
G
E
T
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q5U9X3
867
97118
T217
S
W
V
G
I
I
I
T
D
G
D
Y
G
R
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91685
976
108467
S225
S
Y
V
S
T
I
H
S
E
G
S
Y
G
E
Y
Honey Bee
Apis mellifera
NP_001011624
933
103448
S236
S
Y
V
S
T
V
Y
S
E
G
S
Y
G
E
Y
Nematode Worm
Caenorhab. elegans
Q09630
999
113258
S269
S
Y
V
S
L
V
Y
S
A
D
E
Y
G
E
L
Sea Urchin
Strong. purpuratus
XP_784936
1474
165598
S786
T
Y
V
S
T
V
W
S
S
G
E
Y
G
E
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
27.6
27.6
98.1
N.A.
97.4
97.8
N.A.
88.3
67.9
N.A.
25.5
N.A.
45.7
47
39.9
32.2
Protein Similarity:
100
46.3
46.3
98.9
N.A.
98.5
98.7
N.A.
92.7
82.2
N.A.
43.8
N.A.
61.7
63.3
55.6
43.4
P-Site Identity:
100
0
6.6
100
N.A.
100
100
N.A.
100
100
N.A.
33.3
N.A.
66.6
73.3
53.3
73.3
P-Site Similarity:
100
20
26.6
100
N.A.
100
100
N.A.
100
100
N.A.
73.3
N.A.
80
80
66.6
86.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
0
0
47
0
8
0
0
0
0
0
16
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
16
0
0
0
24
8
54
0
0
0
0
% D
% Glu:
0
0
0
0
0
16
0
0
62
0
16
0
0
77
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% F
% Gly:
0
0
0
16
0
0
0
0
0
77
0
0
85
0
0
% G
% His:
0
0
0
0
0
0
8
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
16
0
8
16
8
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
16
0
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
16
0
0
0
0
0
0
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
16
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
16
0
0
0
16
0
8
0
% R
% Ser:
47
0
0
85
0
0
0
77
8
0
16
0
0
0
16
% S
% Thr:
54
0
0
0
70
0
0
8
0
0
0
0
0
0
47
% T
% Val:
0
0
85
0
0
70
0
0
0
0
16
0
0
0
0
% V
% Trp:
0
8
0
0
0
0
8
0
0
0
0
0
0
0
0
% W
% Tyr:
0
77
0
0
0
0
16
0
0
0
0
85
0
0
16
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _